Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZHX2 Q9Y6X8 zinc fingers and homeoboxes 2 Transcription factor 3.4E-02 0.510 0.654
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
RRAS2 P62070 RAS related 2 Enzyme modulator 0.97 0.656 0.500
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
RNASE3 P12724 ribonuclease A family member 3 0.490 0.808
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
MIR223 microRNA 223 0.433 0.808
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923